vctsOnce a cell loses balance and transforms into a tumor, it can be considered “gone crazy. it begins to proliferate indiscriminately and no longer responds to any control. Genetic mutations caused by smoking Today that allow us to identify and quantify mutations. Interesting results were published in 2016, in the journal Science , by Dr. Ludmil B. Alexandrov and his colleagues. The study involved more than 5000 patients, both smokers and non-smokers. And all types of cancer associated with smoking were considered . The study investigated the mutations present in all. Patients and their annual rate based on an average consumption of 20 cigarettes per day.
The mutations found were classified
A total of 20 groups. You can think of each group as a Belgium Phone Number Data characteristic molecular signature of the tumor. The study revealed that smoking is responsible for the. Onset of 5 groups of mutations in particular, and that in some tumors. The association is with only one group of mutations, while in other tumors it is with multiple groups. In the future, this will allow us to better understand through which. Biological mechanism smoking acts to trigger the process of tumorigenesis. Meanwhile, what is clear is that smoking increases the risk of developing various tumors, even in tissues not directly exposed to smoking, due to the increase in the total mutation rate.
A year are able to cause 150 mutations
Just to give an idea: 20 cigarettes a day for belonging to the Brazil Phone Number List group of mutations typical of lung adenocarcinomas and 50 mutations belonging to the groups of mutations typical of all other tumors. Anyone who stops smoking within ten years reduces the risk of cancer by 100%. The study cited was the first to literally deal with mutations, but it has been known for a long time that cigarette smoking predisposes to the development of cancer. In particular, the more you smoke or are exposed to smoke – because, yes, even passive smoking causes damage – the higher the risk.
