What are the new therapeutic frontiers

Non steroidal anti inflammatory drugs NSAIDs   to control pain   and immunosuppressive drugs. To control the progress of the disease by suppressing the action of. The immune system – including antimalarial. methotrexate and azathioprine. For some years now. The use of biological drugs based on monoclonal antibodies had already broadened the therapeutic prospects. Despite this. the progression of the disease is almost inevitable and. Over the years. recurrent inflammation can lead to a significant degree of disability. Unfortunately. the disease is not curable. being a chronic pathology. It is not possible to obtain a cure. However. it would seem that today it is possible to block its progression through the use of innovative biological drugs.

The combined action of Etanercept

This is confirmed by the effectiveness demonstrated by  . a biological drug. with methotrexate . In particular. Etanercept is a soluble TNF  Tumor France Telegram Number Data Necrosis Factor  receptor. which binds to TNF. making it biologically inactive and causing a significant reduction in inflammatory activity. Etanercept. therefore. plays a crucial role in regulating the activity of immune system cells . In addition to rheumatoid arthritis. we remind you that Etanercept has already been approved in Italy for the treatment of various inflammatory diseases. including psoriasis. psoriatic arthritis.

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Juvenile arthritis and pediatric psoriasis

Ankylosing spondylitis. polyarticular . in plates. Methotrexate. on the other hand. is able to inhibit the entire synthesis of purine bases which   together with Canada Phone Number List pyrimidine bases   are the molecules constituting the double strand of DNA. By inhibiting the synthesis of purine bases. methotrexate is therefore able to inhibit the synthesis of DNA and RNA and. consequently. inhibits protein synthesis leading to cell death. it is therefore an anti tumor chemotherapy. However. thanks to its anti inflammatory and immunomodulatory action. methotrexate can be used   at low doses   in the treatment of inflammatory and/or autoimmune diseases and. for this reason. it is the drug of choice in the treatment of rheumatoid arthritis In short.

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