vctsNot everyone knows that the time of day in which a given. Drug is taken influences the effectiveness of the medicine itself. Even fewer people are aware of the existence. That is, the branch of pharmacology that deals with studying the optimal times for taking drugs . Let’s see together what it is. Chrono pharmacology: your medicine at any time For example. From chrono pharmacology studies , it has emerged that in Addison’s disease, characterized by a reduced secretion of hormones at.
The adrenocortical level
The optimal administration of cortisone involves Australia Phone Number Data taking two. Doses of cortisone at 7 am and 11 pm compared to 3 daily doses taken with meals. Then, it seems that the nephrotoxicity of cisplatin. A widespread and well-known anti-tumor drug, is significantly reduced if the antineoplastic is administered from 5pm to 6pm. Similarly, the toxicity of doxorubicin, another antineoplastic, appears to be limited where the chemotherapy is administered in early hours of the morning.
The drug affects its effectiveness
However, the importance of chrono pharmacology emerges Belgium Phone Number List clearly when analyzing some experiments carried out on rats relating to phenobarbital, a molecule with an antiepileptic action belonging to the barbiturate family: the moment of administration of so much so that, by varying the At the time of day when the rats took the drug, the mortality of these animals ranged from 0 to 100. It is worth highlighting that today science has not yet explained exactly why the time of taking a drug influences its effectiveness.
